What is the difference between gaba and phenibut

Phenibut is not licenced for use in the European Union, Australia or the United States due to safety concerns. Although phenibut is commercially available in few countries around the world, aside from Russia, a recent study showed that 48 unrelated internet suppliers sold phenibut from the United Kingdom, United States, China, Australia and Canada. In initial publications , phenibut was known as phenigamma. The drug used to be included in medical kits for cosmonauts on Russian space flights due to the reports of enhanced cognition and high tranquilising properties.

Side effects of phenibut are generally linked to its central nervous system depressant effects, such as sedation and problems with breathing. There is currently limited information about phenibut. Read more: Explainer: how do drugs work? These include gastrointesinal symptoms nausea, vomiting, diarrhoea , central nervous system symptoms insomnia, confusion, euphoria, depression, hallucinations , and visual disturbances and musculoskeletal symptoms such as tremors.

Users of phenibut can also develop tolerance within days, needing more of the drug to feel the same effects. This can increase the risk of adverse effects. Users may develop withdrawal effects, such as severe rebound anxiety and insomnia, when they stop taking the drug.

The above paper goes on to state:. Comparison of phenibut with piracetam and diazepam reveals similarities and differences in their pharmacological and clinical effects.

There is research showing that physical dependence can develop, including tolerance and withdrawal, and adverse symptoms can be similar to benzodiazepines: Phenibut Dependence. We present a case of a patient who used phenibut to self-medicate anxiety, insomnia and cravings for alcohol.

While phenibut was helpful initially, the patient developed dependence including tolerance, significant withdrawal symptoms within h of last use and failure to fulfil his roles at work and at home. He finally sought medical assistance in our addictions clinic. We have gradually, over the course of 9 weeks, substituted phenibut with baclofen, which has similar pharmacological properties, and then successfully tapered the patient off baclofen.

This required approximately 10 mg of baclofen for each gram of phenibut. They only use it if really needed. And some practitioners will say they pulse. When I read all that I was just horrified. Food Mood Expert Trudy Scott is a certified nutritionist on a mission to educate and empower anxious individuals worldwide about natural solutions for anxiety, stress and emotional eating. Trudy is passionate about sharing the powerful food mood connection because she experienced the results first-hand, finding complete resolution of her anxiety and panic attacks.

I live in Wollongong, which is around 80 kilometers south of Sydney. She is suffering from anxiety and she needs to calm down so that she can sleep and eat properly.

Otherwise, please let me know if I can get them from somewhere else or you could even recommend a brand that you think is good. You could have her try the Australian products. Keep in mind that they are powder and the website recommends much high doses that I do. My husband has been quite stressed and tensed with work issues for a long time now and as for myself I am constanltly hunching my shoulders and feeling them tensed and tight plus I also have Hashimoto and few other issues.

We tried again around 11 pm before going to bed and both had a completely sleepless night, so much so that around 4 am we took some Stilnox just so that we get a couple of hours sleep.

Not sure why that has been the case. Not sure how long I shall continue to persevere or if I need to change some of my supplements. I sometimes have no problem falling a sleep though sometimes that is still a problem , but for the most part I have a problem staying asleep. Hope this info helps in any way…. They have very cheap shipping to Australia and typically an order gets here in about a week.

You can also pay in Australian dollars. Apart from them being cheaper, they have a much larger range of products than you can get in Australia and they also list ALL the ingredients on every supplement.

Wonderful informative post Trudy, thank you for bringing this into the light. Having said that, I slept 7 hours right through last night with only some magnesium, B6, B3 and some adaptogens… There is hope!

Thanks for sharing Drew. The reason phenibut is so popular is that it does work. Would you please share more on this? The initial response in the first couple of weeks was great, especially a couple of hours after taking it.

However, after a few weeks it was the reaction on the following day of taking it that kicked me in the butt, literally. On the following day I began to feel very low, groggy and spaced out, almost like a hangover and then during the following night I began having brutal insomnia — a complete turn around from the night before.

A kind of rebound response. Other side effects included mood swings, irritability, rebound anxiety, panic, loss of short term memory, total and utter loss of any form of libido and constipation! I literally cannot go out at night any more to shows, dinner with friends or whatever — I am way too sensitive and it takes me hours, often days to wind down which in turn wrecks my sleep.

This has become worse and worse as the years progress… All quite daunting to be honest. Spending time in nature is my temporary saviour. Dear Drew, I was touched to read your post and hope you can find true and lasting relief. If you have not already done so, please give thought to having a:. Whole blood histamine test to know your methylation status.

From your description, you could possibly be under or over methylated both of which can cause a range of disabling symptoms. Serum blood copper test. Some of us have an unknown excess of copper which is a disrupter of neurotransmitters.

Pyroluria test. As a follower of Trudy, I imagine you have already tested yourself via urine test or questionnaire to know if you have pyroluria.

No doubt, your trauma sadly has taken a toll on you — as it would on all of us. If balanced, we are best equipped to cope. If unbalanced, we are poorly equipped to cope, often thru no fault of our own. And best of all, with folks like Trudy, Peter Bongiorno, William Walsh, we can thru nutrients rebalance our systems and achieve greater health both physical and emotional.

Best wishes! Hello L and thank you so much for writing to me and for your kind and helpful advice and suggestions which I have noted. Warm wishes to you too. The book covers depression but also anxiety, pyroluria and much more. The author explains how much we are our biochemistry. Also, she writes with great compassion and offers encouragement and hope to her readers.

Her book is an enlightening, informative and uplifting read — as are the books of Peter Bongiorno and William J. One key point that I have come to understand is that it is very common for us to have more than one type of imbalance in our biochemistry.

As such, healing will come when all the necessary corrections are made. For example, one might have both pyroluria and under methylation. One would then need to be on both a pyroluria and under methylation supplement program to fully heal. Thanks L for your kind words for me and offering ideas for Drew. I also love Joan Mathews Larson and her work!

Please share links to products and I can comment. With the help of your excellent book, I learned I have pyroluria and I learned how to start to manage it. I have also had good results with opening a GABA mg capsule and putting a small amount on my tongue. In the early days of taking the B6 and Zinc my body desperately needed, I found I also needed to raise my serotonin. For my particular biochemistry, I found 5HTP to provide better relief than tryptophan during epsiodes of anxiety.

I also now need to add 5HTP only occasionally. I have found that amino acids do indeed work. They also provide critical relief for anxiety while we are working to correct our underlying biochemical imbalances and nutrient deficiencies. Trudy, I am so grateful for your book and blog. Thank you! Thanks too for offering inspiration and hope to others reading this! I had read that you were reluctant to use phenibut from previous blog posts, but was delighted to see this post offering more insight into why.

Thanks for the info! I learn so much from you. Is this natural and non-addictive. I have so suffered from anxiety my whole life. I quit college because of it and it has nearly ruined my life in so many respects. There are many possible causes of anxiety but doing a trial of GABA is a quick and affordable way to determine if it is one of the causes. Hello Trudy, I have chronic insomnia with high cortisol levels.

Recently done tests have shown low GABA, high glutamate, high copper, low lithium levels. Is there a particular brand of GABA you recommend over others? I have trouble staying asleep more than 4 hours at a stretch. Thank you in advance. Generally it seems more effective than pharmaGABA.

Timed-release melatonin is also something I will consider. Of course diet is big — protein at breakfast for blood sugar control, no gluten, no caffeine, no sugar and addressing gut health and SIBO too.

Thanks for the prompt reply, Trudy! Any GABA brand in particular that you prefer? There is also plenty on the blog about this. GABA supplements, like so many others, are proving to work at best as a placebo. GABA itself very poorly crosses the blood brain barrier. It would take massive doses for most people to get results. Phenibut, athough addictive, works wonders at even low doses and easily crosses the blood brain barrier.

Also, much like so many chemicals and hormones in our body, there needs to be synergy with other chemicals. Anyway, It seems to me there is more to this topic that people should be made aware of. Remember, that placebo is VERY powerful and most likely any GABA supplements are only taking advantage of that brain feature as it has not had clinical trials yet.

The number of success stories seem to model placebo. I myself take Phenibut at mg small dose when I have some excitability.

Comparison of phenibut with piracetam and diazepam reveals similarities and differences in their pharmacological and clinical effects. Phenibut is widely used in Russia to relieve tension, anxiety, and fear, to improve sleep in psychosomatic or neurotic patients; as well as a pre- or post-operative medication.

It is also used in the therapy of disorders characterized by asthenia and depression, as well as in post-traumatic stress, stuttering and vestibular disorders.